E-ISSN 2218-6050 | ISSN 2226-4485
 

Research Article


Effects of experimental hepatic steatosis on apelin and various biochemical parameters in male white rabbits

Rana Suhail Al-juwary, Muntaha Mahmood Al-kattan.


Abstract
Background:
Hepatic steatosis is the second most prevalent liver disease following viral hepatitis, and its incidence is increasing rapidly, posing a significant threat to human health.

Aim:
The research aimed to identify natural treatment methods that reduce the risk of experimental hepatic steatosis with triton by answering the following questions:
1. Do polyphenols extracted from strawberries reduce the risk of experimental hepatic steatosis in rabbits?
2. Do omega-3 extracted from almonds reduce the risk of experimental hepatic steatosis in rabbits?
3. Is giving Omega-3,Vit. E considered the optimal treatment for hepatic steatosis?

Methods:
This study aimed to assess the effects of strawberry polyphenols, omega-3 from almonds, omega-3, and vitamin E on reducing the risk of Triton-induced liver steatosis. The experiment involved 100 male rabbits (10-12 months old, 1150-1350 g) divided randomly into the following 10 groups: control group , Triton (300 mg/kg body mass) group, strawberry polyphenols group, strawberry polyphenols with Triton group, almond Omega-3 group, almond Omega-3 with Triton group, strawberry polyphenols with almond Omega-3 group, strawberry polyphenols with almond Omega-3 with Triton group, Omega-3, Vit. E group, and Omega-3 , Vit. E with Triton group. Dosing occurred daily for 4 months.

Results:
The results of the study indicated a significant increase in the levels of TG, TC, LDL-c, and VLDL-c in the group of rabbits treated with Triton compared with the other groups, while these parameters decreased in the groups treated with strawberry polyphenols, omega-3 from almonds, omega-3, and vitamin E. In addition, the levels of HDL-c, PON-1 activity, and apelin concentration decreased in the group treated with Triton but increased in the groups receiving strawberry polyphenols, omega-3 from almonds, omega-3, and vitamin E, at a probability level (P≤0.01).

Conclusion:
These results suggest that polyphenols extracted from strawberries, Omega-3 extracted from almonds, and Omega-3, Vit. E is a suitable treatment for hepatic steatosis.

Key words: Almond, Apelin, Fatty liver, Strawberry, Triton


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Rana Suhail AL-Juwary
Articles by Muntaha Mahmood AL-Kattan
on Google
on Google Scholar


How to Cite this Article
Pubmed Style

Al-juwary RS, Al-kattan MM. Effects of experimental hepatic steatosis on apelin and various biochemical parameters in male white rabbits. Open Vet J. 2025; 15(1): 211-221. doi:10.5455/OVJ.2025.v15.i1.20


Web Style

Al-juwary RS, Al-kattan MM. Effects of experimental hepatic steatosis on apelin and various biochemical parameters in male white rabbits. https://www.openveterinaryjournal.com/?mno=218614 [Access: March 12, 2025]. doi:10.5455/OVJ.2025.v15.i1.20


AMA (American Medical Association) Style

Al-juwary RS, Al-kattan MM. Effects of experimental hepatic steatosis on apelin and various biochemical parameters in male white rabbits. Open Vet J. 2025; 15(1): 211-221. doi:10.5455/OVJ.2025.v15.i1.20



Vancouver/ICMJE Style

Al-juwary RS, Al-kattan MM. Effects of experimental hepatic steatosis on apelin and various biochemical parameters in male white rabbits. Open Vet J. (2025), [cited March 12, 2025]; 15(1): 211-221. doi:10.5455/OVJ.2025.v15.i1.20



Harvard Style

Al-juwary, R. S. & Al-kattan, . M. M. (2025) Effects of experimental hepatic steatosis on apelin and various biochemical parameters in male white rabbits. Open Vet J, 15 (1), 211-221. doi:10.5455/OVJ.2025.v15.i1.20



Turabian Style

Al-juwary, Rana Suhail, and Muntaha Mahmood Al-kattan. 2025. Effects of experimental hepatic steatosis on apelin and various biochemical parameters in male white rabbits. Open Veterinary Journal, 15 (1), 211-221. doi:10.5455/OVJ.2025.v15.i1.20



Chicago Style

Al-juwary, Rana Suhail, and Muntaha Mahmood Al-kattan. "Effects of experimental hepatic steatosis on apelin and various biochemical parameters in male white rabbits." Open Veterinary Journal 15 (2025), 211-221. doi:10.5455/OVJ.2025.v15.i1.20



MLA (The Modern Language Association) Style

Al-juwary, Rana Suhail, and Muntaha Mahmood Al-kattan. "Effects of experimental hepatic steatosis on apelin and various biochemical parameters in male white rabbits." Open Veterinary Journal 15.1 (2025), 211-221. Print. doi:10.5455/OVJ.2025.v15.i1.20



APA (American Psychological Association) Style

Al-juwary, R. S. & Al-kattan, . M. M. (2025) Effects of experimental hepatic steatosis on apelin and various biochemical parameters in male white rabbits. Open Veterinary Journal, 15 (1), 211-221. doi:10.5455/OVJ.2025.v15.i1.20