E-ISSN 2218-6050 | ISSN 2226-4485
 

Case Report


Platelet-rich plasma application for the management of early-stage Canine Legg-calvé-perthes disease: A clinical case report

Viktoras Sinkevičius, Matas Klupšas, Dmitrij Kvitka, Martinas Jankauskas.


Abstract
Background:
Legg-Calvé-Perthes Disease (LCPD) is characterized by ischemic necrosis of the femoral head, primarily affecting small breed dogs.

Case Description:
An 11-month-old, female Toy Poodle presented with hindlimb lameness due to LCPD, previously treated unsuccessfully with NSAIDs. Platelet-Rich Plasma (PRP) was administered intra-articularly. Clinical evaluations included lameness scoring, range of motion (ROM), thigh girth measurements, and radiographic assessment.

Conclusion:
PRP administration resulted in significant clinical improvement, reduction in lameness, pain relief, cessation of bone lysis, and increased muscle mass by day 44 post-treatment.

Key words: Canine; Legg-Calvé-Perthes disease; Platelet-rich plasma; PRP; Orthopedic.


 
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How to Cite this Article
Pubmed Style

Sinkevičius V, Klupšas M, Kvitka D, Jankauskas M. Platelet-rich plasma application for the management of early-stage Canine Legg-calvé-perthes disease: A clinical case report. Open Vet. J.. 2025; 15(10): 5415-5419. doi:10.5455/OVJ.2025.v15.i10.60


Web Style

Sinkevičius V, Klupšas M, Kvitka D, Jankauskas M. Platelet-rich plasma application for the management of early-stage Canine Legg-calvé-perthes disease: A clinical case report. https://www.openveterinaryjournal.com/?mno=260289 [Access: November 10, 2025]. doi:10.5455/OVJ.2025.v15.i10.60


AMA (American Medical Association) Style

Sinkevičius V, Klupšas M, Kvitka D, Jankauskas M. Platelet-rich plasma application for the management of early-stage Canine Legg-calvé-perthes disease: A clinical case report. Open Vet. J.. 2025; 15(10): 5415-5419. doi:10.5455/OVJ.2025.v15.i10.60



Vancouver/ICMJE Style

Sinkevičius V, Klupšas M, Kvitka D, Jankauskas M. Platelet-rich plasma application for the management of early-stage Canine Legg-calvé-perthes disease: A clinical case report. Open Vet. J.. (2025), [cited November 10, 2025]; 15(10): 5415-5419. doi:10.5455/OVJ.2025.v15.i10.60



Harvard Style

Sinkevičius, V., Klupšas, . M., Kvitka, . D. & Jankauskas, . M. (2025) Platelet-rich plasma application for the management of early-stage Canine Legg-calvé-perthes disease: A clinical case report. Open Vet. J., 15 (10), 5415-5419. doi:10.5455/OVJ.2025.v15.i10.60



Turabian Style

Sinkevičius, Viktoras, Matas Klupšas, Dmitrij Kvitka, and Martinas Jankauskas. 2025. Platelet-rich plasma application for the management of early-stage Canine Legg-calvé-perthes disease: A clinical case report. Open Veterinary Journal, 15 (10), 5415-5419. doi:10.5455/OVJ.2025.v15.i10.60



Chicago Style

Sinkevičius, Viktoras, Matas Klupšas, Dmitrij Kvitka, and Martinas Jankauskas. "Platelet-rich plasma application for the management of early-stage Canine Legg-calvé-perthes disease: A clinical case report." Open Veterinary Journal 15 (2025), 5415-5419. doi:10.5455/OVJ.2025.v15.i10.60



MLA (The Modern Language Association) Style

Sinkevičius, Viktoras, Matas Klupšas, Dmitrij Kvitka, and Martinas Jankauskas. "Platelet-rich plasma application for the management of early-stage Canine Legg-calvé-perthes disease: A clinical case report." Open Veterinary Journal 15.10 (2025), 5415-5419. Print. doi:10.5455/OVJ.2025.v15.i10.60



APA (American Psychological Association) Style

Sinkevičius, V., Klupšas, . M., Kvitka, . D. & Jankauskas, . M. (2025) Platelet-rich plasma application for the management of early-stage Canine Legg-calvé-perthes disease: A clinical case report. Open Veterinary Journal, 15 (10), 5415-5419. doi:10.5455/OVJ.2025.v15.i10.60