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Case Report


Combined ophthalmic therapy and equine placental extract supplementation to treat corneal perforation in geriatric cats: A case report in the absence of surgical intervention

Takae Natori, Eiichi Hirano.


Abstract
Background:
Environmental changes affecting pet animals, along with an increase in age-related conditions and diseases among pets, have become increasingly evident. Despite this trend, there remains a paucity of research on therapeutic approaches for geriatric companion animals.

Case Description:
The case report describes a 19-year-old spayed female cat that was diagnosed with chronic renal failure and recurrent corneal disease. Surgical intervention was not pursued at the owner’s request, leaving medical management as the only viable option. The patient’s corneal condition deteriorated, culminating in corneal perforation. Upon initiation of equine placental extract supplementation alongside medical treatment, substantial improvements were observed in hyperaemia, ocular discomfort, and additional corneal manifestations, including wound severity, ocular discharge, photophobia, lacrimation, and blepharospasm.

Conclusion:
The integration of medical therapy with placental extract supplementation may represent a novel therapeutic alternative for geriatric cats ineligible for surgical intervention.

Key words: Corneal perforation; Geriatric cat; Placental extract; Supplementation.


 
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Pubmed Style

Natori T, Hirano E. Combined ophthalmic therapy and equine placental extract supplementation to treat corneal perforation in geriatric cats: A case report in the absence of surgical intervention. Open Vet. J.. 2025; 15(10): 5420-5426. doi:10.5455/OVJ.2025.v15.i10.61

Web Style

Natori T, Hirano E. Combined ophthalmic therapy and equine placental extract supplementation to treat corneal perforation in geriatric cats: A case report in the absence of surgical intervention. https://www.openveterinaryjournal.com/?mno=260630 [Access: November 10, 2025]. doi:10.5455/OVJ.2025.v15.i10.61

AMA (American Medical Association) Style

Natori T, Hirano E. Combined ophthalmic therapy and equine placental extract supplementation to treat corneal perforation in geriatric cats: A case report in the absence of surgical intervention. Open Vet. J.. 2025; 15(10): 5420-5426. doi:10.5455/OVJ.2025.v15.i10.61


Vancouver/ICMJE Style

Natori T, Hirano E. Combined ophthalmic therapy and equine placental extract supplementation to treat corneal perforation in geriatric cats: A case report in the absence of surgical intervention. Open Vet. J.. (2025), [cited November 10, 2025]; 15(10): 5420-5426. doi:10.5455/OVJ.2025.v15.i10.61


Harvard Style

Natori, T. & Hirano, . E. (2025) Combined ophthalmic therapy and equine placental extract supplementation to treat corneal perforation in geriatric cats: A case report in the absence of surgical intervention. Open Vet. J., 15 (10), 5420-5426. doi:10.5455/OVJ.2025.v15.i10.61


Turabian Style

Natori, Takae, and Eiichi Hirano. 2025. Combined ophthalmic therapy and equine placental extract supplementation to treat corneal perforation in geriatric cats: A case report in the absence of surgical intervention. Open Veterinary Journal, 15 (10), 5420-5426. doi:10.5455/OVJ.2025.v15.i10.61


Chicago Style

Natori, Takae, and Eiichi Hirano. "Combined ophthalmic therapy and equine placental extract supplementation to treat corneal perforation in geriatric cats: A case report in the absence of surgical intervention." Open Veterinary Journal 15 (2025), 5420-5426. doi:10.5455/OVJ.2025.v15.i10.61


MLA (The Modern Language Association) Style

Natori, Takae, and Eiichi Hirano. "Combined ophthalmic therapy and equine placental extract supplementation to treat corneal perforation in geriatric cats: A case report in the absence of surgical intervention." Open Veterinary Journal 15.10 (2025), 5420-5426. Print. doi:10.5455/OVJ.2025.v15.i10.61


APA (American Psychological Association) Style

Natori, T. & Hirano, . E. (2025) Combined ophthalmic therapy and equine placental extract supplementation to treat corneal perforation in geriatric cats: A case report in the absence of surgical intervention. Open Veterinary Journal, 15 (10), 5420-5426. doi:10.5455/OVJ.2025.v15.i10.61


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